ML-007C Phase 2 trial meets primary endpoint in Schizophrenia (MapLight Therapeutics)

Nasdaq: MPLT−73.66% 24h move
Price before$36.56Jul 24, 2026, 4:00 PM ET
First trade after$22.30Jul 27, 2026, 7:11 AM ET
24h later$9.63Jul 28, 2026, 7:05 AM ET

Complete Announced during: Premarket · announced Mon 7:07a ET (premarket); before = Fri close; first trade Mon 7:11a ET; time = SEC 8-K acceptance

MapLight Therapeutics (Nasdaq: MPLT) reported topline results from a Phase 2 trial of ML-007C in schizophrenia on July 27, 2026. The company said the trial met its primary endpoint.

Trial details

Drug
ML-007C
Phase
Phase 2
Result
Met endpointThe trial met its primary endpoint, with the 210/3 mg twice-daily (BID) dose demonstrating a statistically significant and clinically meaningful reduction in Positive and Negative Syndrome Scale (PANSS) total score compared to placebo at Week 5.
Safety
Safety and Tolerability ML-007C-MA was generally well tolerated across all doses studied.
Sponsor
MapLight Therapeutics Nasdaq: MPLT
Dates
Announced Jul 27, 2026, 7:07 AM ET (SEC 8-K filing time)

About this trial

This Phase 2 trial tested ML-007C in Schizophrenia. MapLight Therapeutics reported that the trial met its primary endpoint.

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